ECLS Lab

Research in our laboratory focuses on applying ECLS technology to range of clinical problems and requires a deep understanding of the physiology of many processes and pathways. As examples, our cardiac arrest work explores the relationship between blood clot formation and inflammation. This has led us to look at the potentially beneficial role of neutrophil extracellular traps and novel nitric-oxide-eluting device components. Our work on an artificial placenta aims to replicate the normal physiological gas exchange processes taking place in utero so the fetus’ developing lungs can continue to mature without the complications of mechanical ventilation. Our work to preserve donor organs outside the body investigates many pathways of organ injury that result from current preservation methods, including hemoperfusion and inflammation.