Koutmou Lab

The research in our lab focuses on investigating the biological consequences of ribosome encountering faulty mRNA. Part of our research is to study how post-transcriptional modifications alter mRNA structure, translation, and stability, and how the ribonucleoprotein content of different mRNAs is controlled by their modification status. We employ molecular biology, biochemical, and genome-wide (ribosome profiling) techniques in our work. Some of the techniques include molecular cloning, protein purification by FPLC, reconstituted in vitro translation, transient kinetics, ribosome profiling, western blotting etc. {Originally certified gold: August 10, 2017}